Design of treatment trials for functional gastrointestinal disorders

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Design of treatment trials for functional gastrointestinal disorders.

This document addresses the design of trials to assess the efficacy of new treatments for functional gastrointestinal disorders (FGID), emphasizing trials in irritable bowel syndrome and dyspepsia, because most research has been undertaken in these conditions. The double-blind, randomized, placebo-controlled, parallel group trial remains the preferred design. Randomized withdrawal designs, alth...

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Treatment of Functional Gastrointestinal Disorders in Children and Future Challenges

Functional gastrointestinal disorders (FGIDs) are a common problem in children. These disorders in children are classified into the following categories according to the ROME III classification: Functional Dyspepsia, Irritable bowel syndrome (IBS), Abdominal Migraines, Childhood Functional abdominal pain (FAP), Childhood functional abdominal pain syndrome and functional constipation. FGIDs are ...

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treatment of functional gastrointestinal disorders in children and future challenges

functional gastrointestinal disorders (fgids) are a common problem in children. these disorders in children are classified into the following categories according to the rome iii classification: functional dyspepsia, irritable bowel syndrome (ibs), abdominal migraines, childhood functional abdominal pain (fap), childhood functional abdominal pain syndrome and functional constipation. fgids are ...

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Functional Gastrointestinal Disorders

Los trastornos funcionales digestivos hacen parte de la patología gastrointestinal pediátrica. Son una combinación de síntomas gastrointestinales crónicos y recurrentes inexplicables secundarias a anomalías estructurales o bioquímicas. Involucran un espectro de entidades variadas, algunas de ellas consideradas como normales en el desarrollo del niño, y en las que los factores anatómicos, y afec...

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Childhood functional gastrointestinal disorders.

This is the first attempt at defining criteria for functional gastrointestinal disorders (FGIDs) in infancy, childhood, and adolescence. The decision-making process was as for adults and consisted of arriving at consensus, based on clinical experience. This paper is intended to be a quick reference. The classification system selected differs from the one used in the adult population in that it ...

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ژورنال

عنوان ژورنال: Gut

سال: 1999

ISSN: 0017-5749

DOI: 10.1136/gut.45.2008.ii69